SERZONE
On January 9, 2002, Bristol-Myers Squibb Co. issued a manufacturer's warning
advising health care providers that cases of life-threatening hepatic
failure have been reported in patients treated with Serzone, an anti depressant
drug. The warning indicates that numerous persons have or will suffer
liver failure, and that current estimates of the rate of liver failure
associated with Serzone use are about 3-4 times the estimated background
of liver failure.
On
December 7, 2001, the U.S. Food and Drug Administration told Bristol-Myer
Squibb to include a so-called black box warning on labels of the anti-depressant
drug Serzone® informing patients that life-threatening liver damage
can occur when using the drug. Cases of liver failure leading to transplant
and/or death in patients have been reported.
symptoms:
Jaundice
Discolored urine
Appetite loss
Nausea
Abdominal pain
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